Articles by author - Michal Siller

The influence of rosuvastatin on liver microsomal CYP2C6 in hereditary hypertriglyceridemic rat.

Vecera R, Zacharová A, Siller M, Matuskova Z, Skottová N, Anzenbacherová E, Anzenbacher P.

Journal Article 2012; 33(Suppl 3): 48-52 PubMed PMID: 23353843  Keywords:  Animals, Aryl Hydrocarbon Hydroxylases:antagonists & inhibitors, Cholesterol, Dietary:pharmacology, Cytochrome P-450 CYP2C9, Cytochrome P450 Family 2, Fluorobenzenes:pharmacology, Gene Expression Regulation, Enzymologic:drug effects, Humans, Hydroxymethyl.    Citation

OBJECTIVES: The aim of this study was to investigate whether rosuvastatin affects expression and activity of rat CYP2C6. This cytochrome P.....

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Effects of Lactobacillus casei on the expression and the activity of cytochromes P450 and on the CYP mRNA level in the intestine and the liver of male rats.

Matuskova Z, Siller M, Tunkova A, Anzenbacherova E, Zacharova A, Tlaskalova-Hogenova H, Zidek Z, Anzenbacher P.

Evaluation Studies 2011; 32(Suppl 1): 8-14 PubMed PMID: 22167211  Keywords:  Animals, Aryl Hydrocarbon Hydroxylases:genetics, Cytochrome P-450 CYP1A2, Cytochrome P-450 CYP2E1:genetics, Cytochrome P-450 CYP3A:genetics, Cytochrome P-450 Enzyme System:genetics, Cytochrome P450 Family 2, Cytochromes:genetics, Enzyme Activation:drug ef.    Citation

OBJECTIVES: The aim of the study was to find whether probiotic Lactobacillus casei influences the expression or the activity of cytochrome.....

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Effects of probiotic Escherichia coli Nissle 1917 on expression of cytochromes P450 along the gastrointestinal tract of male rats.

Matuskova Z, Tunkova A, Anzenbacherova E, Vecera R, Siller M, Tlaskalova-Hogenova H, Zidek Z, Anzenbacher P.

Journal Article 2010; 31(Suppl 2): 46-50 PubMed PMID: 21187832  Keywords:  Animals, Aryl Hydrocarbon Hydroxylases:metabolism, Colon:enzymology, Cytochrome P-450 CYP3A:metabolism, Cytochrome P-450 Enzyme System:metabolism, Duodenum:enzymology, Escherichia coli, Gastrointestinal Tract:enzymology, Male, Models, Animal, Probiotics:p.    Citation

OBJECTIVES: The aim of the study was to find whether probiotic Escherichia coli Nissle 1917 O6:K5:H1 (EcN) influences the expression of cy.....

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Interspecies comparison of the glucuronidation processes in the man, monkey, pig, dog and rat.

Matal J, Jancova P, Siller M, Masek V, Anzenbacherova E, Anzenbacher P.

Comparative Study 2008; 29(5): 738-743 PubMed PMID: 18987594  Keywords:  Animals, Dogs, Glucuronides:metabolism, Glucuronosyltransferase:metabolism, Haplorhini, Humans, Kinetics, Microsomes, Liver:enzymology, Protective Agents:metabolism, Rats, Silymarin:metabolism, Species Specificity, Swine,.    Citation

OBJECTIVES: The study of interspecies differences in glucuronidation processes in the man, monkey, pig, dog and rat using liver microsomal.....

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