Articles by author - Karel Soucek

Preparation and application of anti-peptide antibodies for detection of orphan cytochromes P450.

Hodek P, Hrdinova J, Macova I, Soucek P, Mrizova I, Burdova K, Kizek R, Hudecek J, Stiborova M.

Journal Article 2015; 36(Suppl 1): 38-45 PubMed PMID: 26757124  Keywords:  Animals, Antibodies:immunology, Antibody Formation, Blotting, Western, Cell Line, Tumor, Chickens, Cytochrome P-450 Enzyme System:immunology, Cytochrome P450 Family 2, Eggs, Electrophoresis, Gel, Two-Dimensional, Enzyme-Linked Immunosorbent Assay, Humans,.    Citation

OBJECTIVES: Cytochromes P450 (CYP) are monooxygenases, which metabolize mostly hydrophobic endogenous and exogenous compounds. CYPs withou.....

Read abstract  Full text PDF

The comparison of impedance-based method of cell proliferation monitoring with commonly used metabolic-based techniques.

Vistejnova L, Dvorakova J, Hasova M, Muthny T, Velebny V, Soucek K, Kubala L.

Comparative Study 2009; 30(Suppl 1): 121-127 PubMed PMID: 20027157  Keywords:  3T3 Cells, Adenosine Triphosphate:metabolism, Animals, Cell Count:methods, Cell Line, Cell Proliferation, Cells, Cultured, Colorimetry, Dermis:cytology, Electric Impedance, Fibroblasts:cytology, Humans, Keratinocytes:cytology, Luminescent Measurements, Mi.    Citation

OBJECTIVES: Determination of cell numbers is a crucial step in studies focused on cytokinetics and cell toxicity. The impedance-based anal.....

Read abstract  Full text PDF

Uveal melanoma in congenital ocular melanocytosis mimicking malignant transformation of the optic disc melanocytoma (a controlled case).

Cihelkova I, Soucek P, Sach J.

Case Reports 2006; 27(6): 729-732 PubMed PMID: 17187021  Keywords:  Diagnosis, Differential, Eye Diseases:congenital, Female, Humans, Melanocytes:pathology, Melanoma:complications, Melanosis:congenital, Middle Aged, Nevus, Pigmented:pathology, Optic Disk:pathology, Optic Nerve Neoplasms:pathology, Uveal Neoplasms:complica.    Citation

: A case of a 57-year old woman with uveal melanoma of the posterior pole arising in the congenital ocular melanocytosis mimicking clinica.....

Read abstract  Full text PDF

Photodynamic therapy with Verteporfin in subfoveal choroidal metastasis of breast carcinoma (a controlled case).

Soucek P, Cihelkova I.

Case Reports 2006; 27(6): 725-728 PubMed PMID: 17187011  Keywords:  Antineoplastic Agents:therapeutic use, Breast Neoplasms:drug therapy, Carcinoma, Medullary:drug therapy, Choroid Neoplasms:drug therapy, Female, Humans, Middle Aged, Palliative Care:methods, Photochemotherapy:methods, Photosensitizing Agents:therapeutic u.    Citation

: A 55-year old woman with growing unilateral subfoveal choroidal metastasis of breast carcinoma was treated by photodynamic therapy (PDT).....

Read abstract  Full text PDF

Chromosomal damage and polymorphisms of DNA repair genes XRCC1 and XRCC3 in workers exposed to cytostatics.

Musák L, Vodicka P, Klimentová G, Soucek P, Hánová M, Mikulková R, Buchancová J, Vodicková L, Poláková V, Péc M.

Journal Article 2006; 27(Suppl 2): 57-60 PubMed PMID: 17159780  Keywords:  Adult, Antineoplastic Agents:toxicity, Chromosomes, Human, DNA Damage, DNA-Binding Proteins:genetics, Female, Gene Frequency, Genetic Predisposition to Disease, Humans, Male, Medical Staff, Hospital, Middle Aged, Occupational Diseases:chemically induced, .    Citation

OBJECTIVES: Medical workers in oncological units have chronically been exposed to low doses of cytostatics (C) with potential consequences.....

Read abstract

Photodynamic therapy with verteporfin in subfoveal amelanotic choroidal melanoma (A controlled case).

Soucek P, Cihelkova I.

Case Reports 2006; 27(1-2): 145-148 PubMed PMID: 16648785  Keywords:  Eye:diagnostic imaging, Eye Neoplasms:diagnostic imaging, Humans, Male, Melanoma, Amelanotic:diagnostic imaging, Middle Aged, Photochemotherapy, Photosensitizing Agents:therapeutic use, Porphyrins:therapeutic use, Ultrasonography,.    Citation

: A 57-year old man with 2.7 mm thick subfoveal amelanotic choroidal melanoma of the right eye was indicated for photodynamic therapy with.....

Read abstract