Articles by author - George B Stefano

The neurobiology of pleasure, reward processes, addiction and their health implications.

Esch T, Stefano G.

Journal Article 2004; 25(4): 235-251 PubMed PMID: 15361811  Keywords:  Behavior, Addictive:physiopathology, Culture, Dopamine:physiology, Endorphins:physiology, Humans, Limbic System:physiology, Motivation, Neurobiology, Pleasure-Pain Principle, Reward,.    Citation

: Modern science begins to understand pleasure as a potential component of salutogenesis. Thereby, pleasure is described as a state or fee.....

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Immunocytes modulate ganglionic nitric oxide release which later affects their activity level.

Stefano G, Mantione K, Jones D, Zhu W, Casares F, Cadet P.

Journal Article 2004; 25(1-2): 57-61 PubMed PMID: 15159684  Keywords:  Animals, Bivalvia, Enzyme Inhibitors:pharmacology, Feedback, Physiological:physiology, Ganglia, Invertebrate:cytology, Interleukin-1:physiology, Leukocytes:drug effects, Lymphocyte Activation:physiology, NG-Nitroarginine Methyl Ester:pharmacology, Neuroim.    Citation

: Pedal ganglia excised and maintained in culture for up to 2 h, release NO at low levels. The range can vary between 0 to 1.1 nM. Non-sti.....

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Chromacin-like peptide in leeches.

Salzet M, Stefano G.

Journal Article 2003; 24(3-4): 227-232 PubMed PMID: 14523362  Keywords:  Amino Acid Sequence, Animals, Dose-Response Relationship, Drug, Enzyme-Linked Immunosorbent Assay, Hemolymph:metabolism, Leeches:metabolism, Lipopolysaccharides:pharmacology, Molecular Sequence Data, Peptides:metabolism, Radioimmunoassay, Spectrometry, Ma.    Citation

: We demonstrate the presence in leech hemolymph of high levels of a peptide recognized by antiserum directed against bovine chromacin. Th.....

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The role of the estrogen in neuroprotection: implications for neurodegenerative diseases.

Cho J, Iannucci F, Fraile M, Franco J, Alesius T, Stefano G.

Journal Article 2003; 24(3-4): 141-147 PubMed PMID: 14523347  Keywords:  Animals, Brain Chemistry:genetics, Estrogens:physiology, Female, Humans, Male, Neurodegenerative Diseases:physiopathology, Receptors, Estrogen:genetics,.    Citation

: In trying to rectify the differences in the risk, onset, and progression of neurodegenerative diseases between men and women, the gonada.....

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The presence of 17-beta estradiol in Mytilus edulis gonadal tissues: evidence for estradiol isoforms.

Zhu W, Mantione K, Jones D, Salamon E, Cho J, Cadet P, Stefano G.

Journal Article 2003; 24(3-4): 137-140 PubMed PMID: 14523346  Keywords:  Animals, Bivalvia:metabolism, Chromatography, High Pressure Liquid, Estradiol:metabolism, Gonads:metabolism, Isomerism, Radioimmunoassay, Reproduction:physiology, Spectrometry, Mass, Electrospray Ionization, Spectrophotometry, Ultraviolet,.    Citation

OBJECTIVES: In earlier studies, we demonstrate that 17-beta -estradiol and an estrogen cell surface receptor can be found on various human.....

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17-beta estradiol down regulates ganglionic microglial cells via nitric oxide release: presence of an estrogen receptor beta transcript.

Stefano G, Zhu W, Mantione K, Jones D, Salamon E, Cho J, Cadet P.

Journal Article 2003; 24(3-4): 130-136 PubMed PMID: 14523345  Keywords:  Animals, Base Sequence, Bivalvia:metabolism, Cell Movement:drug effects, Cloning, Molecular, Down-Regulation:drug effects, Enzyme Inhibitors:pharmacology, Estradiol:pharmacology, Estrogen Receptor beta, Ganglia, Invertebrate:cytology, In Vitro Techniques,.    Citation

OBJECTIVES: In earlier studies we have demonstrated that 17-beta-estradiol and an estrogen cell surface receptor can be found on various h.....

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