Stiborova M, Manhartova Z, Hodek P, Adam V, Kizek R, Eckschlager T, Frei E.
Journal Article 2015; 36(Suppl 1): 22-28 PubMed PMID: 26757112 Keywords: Animals, Antineoplastic Agents:pharmacology, Cell Survival:drug effects, DNA Adducts:drug effects, Ellipticines:pharmacology, HL-60 Cells, Humans, In Vitro Techniques, Liver:drug effects, Micelles, Rats,. CitationOBJECTIVES: The improvements of cancer treatment are the major challenge in oncology research. Nanocarriers are one of the promising appro.....
Stiborova M, Manhartova Z, Hodek P, Adam V, Kizek R, Eckschlager T, Frei E. Cytotoxicity of and DNA adduct formation by ellipticine and its micellar form in human leukemia cells in vitro. Neuro Endocrinol Lett. 2015 Jan; 36(Suppl 1): 22-28
Borek-Dohalska L, Valaskova P, Kubickova B, Sulc M, Kresinova Z, Cajthaml T, Stiborova M.
Journal Article 2015; 36(Suppl 1): 5-12 PubMed PMID: 26757108 Keywords: Animals, Aryl Hydrocarbon Hydroxylases:metabolism, Chromatography, High Pressure Liquid, Cytochrome P-450 CYP1A1:metabolism, Cytochrome P-450 CYP3A:metabolism, Cytochrome P-450 Enzyme System:metabolism, Cytochrome P450 Family 2, Ethinyl Estradiol:metaboli. CitationOBJECTIVES: 17α-Ethinylestradiol (EE2) is an endocrine disruptor that is an ingredient of oral contraceptives. Here, EE2 metabolism catal.....
Borek-Dohalska L, Valaskova P, Kubickova B, Sulc M, Kresinova Z, Cajthaml T, Stiborova M. A study on 17alpha-ethinylestradiol metabolism in rat and Pleurotus ostreatus. Neuro Endocrinol Lett. 2015 Jan; 36(Suppl 1): 5-12
Hodek P, Fousova P, Brabencova E, Moserova M, Pavek P, Anzenbacherova E, Brotanek J, Hudecek J, Frei E, Stiborova M.
Journal Article 2014; 35(Suppl 2): 158-168 PubMed PMID: 25638381 Keywords: Animals, Benzo(a)pyrene:administration & dosage, Carcinogens:administration & dosage, DNA Adducts:administration & dosage, Flavonols:administration & dosage, Male, Rats, Rats, Wistar,. CitationOBJECTIVES: Flavanol dihydromyricetin (DHM) has been shown to counteract acute ethanol (EtOH) intoxication and reduce excessive E.....
Hodek P, Fousova P, Brabencova E, Moserova M, Pavek P, Anzenbacherova E, Brotanek J, Hudecek J, Frei E, Stiborova M. Effect of dihydromyricetin on benzo[a]pyrene activation in rats. Neuro Endocrinol Lett. 2014 Jan; 35(Suppl 2): 158-168
Stiborova M, Levova K, Barta F, Dracinska H, Sulc M, Hodek P, Frei E, Arlt V, Schmeiser H.
Journal Article 2014; 35(Suppl 2): 123-132 PubMed PMID: 25638376 Keywords: Animals, Aristolochic Acids:metabolism, Dicumarol:pharmacology, Enzyme Inhibitors:pharmacology, Humans, Quinone Reductases:metabolism, Rats,. CitationOBJECTIVES: Dicoumarol is known to act as an inhibitor of
NAD(P)H: quinone oxidoreductase (NQO1). T.....
Stiborova M, Levova K, Barta F, Dracinska H, Sulc M, Hodek P, Frei E, Arlt V, Schmeiser H. Dicoumarol inhibits rat NAD(P)H:quinone oxidoreductase in vitro and induces its expression in vivo. Neuro Endocrinol Lett. 2014 Jan; 35(Suppl 2): 123-132
Ječmen T, Ptáčková R, Kavan D, Cerná V, Hodek P, Stiborová M, Hudeček J, Sulc M.
Journal Article 2014; 35(Suppl 2): 114-122 PubMed PMID: 25638375 Keywords: Animals, Aryl Hydrocarbon Hydroxylases:metabolism, Cell Membrane:metabolism, Cytochrome P450 Family 2, Cytochromes b5:metabolism,. CitationOBJECTIVES: The mammalian mixed function oxidase (MFO) system participates in hydroxylation of many hydrophobic endogenous compou.....
Ječmen T, Ptáčková R, Kavan D, Cerná V, Hodek P, Stiborová M, Hudeček J, Sulc M. Quantification of interactions between cytochrome P450 2B4 and cytochrome b5 in a functional membrane complex. Neuro Endocrinol Lett. 2014 Jan; 35(Suppl 2): 114-122
Indra R, Moserova M, Kroftova N, Sulc M, Martinkova M, Adam V, Eckschlager T, Kizek R, Arlt V, Stiborova M.
Journal Article 2014; 35(Suppl 2): 105-113 PubMed PMID: 25638374 Keywords: Benzo(a)pyrene:metabolism, Cytochrome P-450 CYP1A1:metabolism, Cytochromes b5:metabolism, Humans, NADH, NADPH Oxidoreductases:metabolism,. CitationOBJECTIVES: Cytochrome P450 (CYP) 1A1 located in the membrane of endoplasmic reticulum is the most important enzyme in both activ.....
Indra R, Moserova M, Kroftova N, Sulc M, Martinkova M, Adam V, Eckschlager T, Kizek R, Arlt V, Stiborova M. Modulation of human cytochrome P450 1A1-mediated oxidation of benzo[a]pyrene by NADPH:cytochrome P450 oxidoreductase and cytochrome b5. Neuro Endocrinol Lett. 2014 Jan; 35(Suppl 2): 105-113