Sulc M, Mrizova I, Cerna T, Frei E, Eckschlager T, Adam V, Kopeckova K, Stiborova M.
Journal Article 2016; 37(Suppl 1): 95-102 PubMed PMID: 28263536 Keywords: Antineoplastic Agents, Phytogenic:metabolism, Cytochrome P-450 CYP3A:metabolism, DNA Adducts:metabolism, Ellipticines:metabolism, Humans, Liposomes, Microsomes,. CitationOBJECTIVES: Ellipticine is an anticancer agent that functions through multiple mechanisms participating in cell cycle arrest and .....
Sulc M, Mrizova I, Cerna T, Frei E, Eckschlager T, Adam V, Kopeckova K, Stiborova M. Effectiveness of human cytochrome P450 3A4 present in liposomal and microsomal nanoparticles in formation of covalent DNA adducts by ellipticine. Neuro Endocrinol Lett. 2016 Dec; 37(Suppl 1): 95-102
Sulc J, Slaby K, Hlinkova Z, Kolar P, Kozak J, Kriz J.
Journal Article 2016; 37(3): 193-201 PubMed PMID: 27618607 Keywords: Adult, Cervical Cord:injuries, Female, Follow-Up Studies, Humans, Longitudinal Studies, Lung Diseases:etiology, Male, Middle Aged, Muscle Strength, Prospective Studies, Quadriplegia:etiology, Respiratory Function Tests, Respiratory Muscles:physiopathology. CitationOBJECTIVES: Respiratory complications are most common cause of morbidity/mortality in patients with cervical spinal cord injury (cSCI) due.....
Sulc J, Slaby K, Hlinkova Z, Kolar P, Kozak J, Kriz J. Pulmonary dysfunction in patients after cervical spinal cord injury: serial follow-up measurement within the first year post-injury. Neuro Endocrinol Lett. 2016 Jul; 37(3): 193-201
Borek-Dohalska L, Valaskova P, Kubickova B, Sulc M, Kresinova Z, Cajthaml T, Stiborova M.
Journal Article 2015; 36(Suppl 1): 5-12 PubMed PMID: 26757108 Keywords: Animals, Aryl Hydrocarbon Hydroxylases:metabolism, Chromatography, High Pressure Liquid, Cytochrome P-450 CYP1A1:metabolism, Cytochrome P-450 CYP3A:metabolism, Cytochrome P-450 Enzyme System:metabolism, Cytochrome P450 Family 2, Ethinyl Estradiol:metaboli. CitationOBJECTIVES: 17α-Ethinylestradiol (EE2) is an endocrine disruptor that is an ingredient of oral contraceptives. Here, EE2 metabolism catal.....
Borek-Dohalska L, Valaskova P, Kubickova B, Sulc M, Kresinova Z, Cajthaml T, Stiborova M. A study on 17alpha-ethinylestradiol metabolism in rat and Pleurotus ostreatus. Neuro Endocrinol Lett. 2015 Jan; 36(Suppl 1): 5-12
Stiborova M, Levova K, Barta F, Dracinska H, Sulc M, Hodek P, Frei E, Arlt V, Schmeiser H.
Journal Article 2014; 35(Suppl 2): 123-132 PubMed PMID: 25638376 Keywords: Animals, Aristolochic Acids:metabolism, Dicumarol:pharmacology, Enzyme Inhibitors:pharmacology, Humans, Quinone Reductases:metabolism, Rats,. CitationOBJECTIVES: Dicoumarol is known to act as an inhibitor of
NAD(P)H: quinone oxidoreductase (NQO1). T.....
Stiborova M, Levova K, Barta F, Dracinska H, Sulc M, Hodek P, Frei E, Arlt V, Schmeiser H. Dicoumarol inhibits rat NAD(P)H:quinone oxidoreductase in vitro and induces its expression in vivo. Neuro Endocrinol Lett. 2014 Jan; 35(Suppl 2): 123-132
Ječmen T, Ptáčková R, Kavan D, Cerná V, Hodek P, Stiborová M, Hudeček J, Sulc M.
Journal Article 2014; 35(Suppl 2): 114-122 PubMed PMID: 25638375 Keywords: Animals, Aryl Hydrocarbon Hydroxylases:metabolism, Cell Membrane:metabolism, Cytochrome P450 Family 2, Cytochromes b5:metabolism,. CitationOBJECTIVES: The mammalian mixed function oxidase (MFO) system participates in hydroxylation of many hydrophobic endogenous compou.....
Ječmen T, Ptáčková R, Kavan D, Cerná V, Hodek P, Stiborová M, Hudeček J, Sulc M. Quantification of interactions between cytochrome P450 2B4 and cytochrome b5 in a functional membrane complex. Neuro Endocrinol Lett. 2014 Jan; 35(Suppl 2): 114-122
Indra R, Moserova M, Kroftova N, Sulc M, Martinkova M, Adam V, Eckschlager T, Kizek R, Arlt V, Stiborova M.
Journal Article 2014; 35(Suppl 2): 105-113 PubMed PMID: 25638374 Keywords: Benzo(a)pyrene:metabolism, Cytochrome P-450 CYP1A1:metabolism, Cytochromes b5:metabolism, Humans, NADH, NADPH Oxidoreductases:metabolism,. CitationOBJECTIVES: Cytochrome P450 (CYP) 1A1 located in the membrane of endoplasmic reticulum is the most important enzyme in both activ.....
Indra R, Moserova M, Kroftova N, Sulc M, Martinkova M, Adam V, Eckschlager T, Kizek R, Arlt V, Stiborova M. Modulation of human cytochrome P450 1A1-mediated oxidation of benzo[a]pyrene by NADPH:cytochrome P450 oxidoreductase and cytochrome b5. Neuro Endocrinol Lett. 2014 Jan; 35(Suppl 2): 105-113