Oxidative detoxication of carcinogenic 2-nitroanisole by human, rat and rabbit cytochrome P450.

Dracínska H, Miksanová M, Svobodová M, Smrcek S, Frei E, Schmeiser H, Stiborová M.

Journal Article 2006; 27(Suppl 2): 9-13 PubMed PMID: 17159769 Keywords: Adolescent, Adult, Aged, Aniline Compounds:metabolism, Animals, Anisoles:pharmacokinetics, Carcinogens:pharmacokinetics, Child, Child, Preschool, Cytochrome P-450 Enzyme System:metabolism, Female, Humans, In Vitro Techniques, Male, Metabolic Detoxication,.

OBJECTIVES: The detoxifying metabolism of a potent rodent carcinogen, 2-nitroanisole (2-NA) by human, rabbit and rat cytochromes P450 (P45.....

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Severe chronic lithium intoxication in patient treated for bipolar disorder.

Stetkarova I, Bocek V, Gismatullina A, Svobodova Z, Peisker T.

Journal Article 2017; 38(6): 397-400 PubMed PMID: 29298279

OBJECTIVE: Lithium has been long used in psychiatry as an adjuvant treatment for bipolar disorder. Chronic lithium intoxication is very ra.....

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The effect of silver nanoparticles and silver ions on zebrafish embryos (Danio rerio).

Caloudova H, Hodkovicova N, Sehonova P, Blahova J, Marsalek B, Panacek A, Svobodova Z.

Journal Article 2018; 39(4): 299-304 PubMed PMID: 30531708 Keywords: Animals, Embryo, Nonmammalian:drug effects, Gelatin, Lethal Dose 50, Maltose, Nanoparticles, Povidone, Silver:toxicity, Silver Nitrate:toxicity, Zebrafish,.

OBJECTIVES: The aim of this study was to establish and evaluate the mortality rate, hatching rate and observe the presence of sublethal ch.....

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Use of all-male triploid population of zebrafish (Danio rerio) for evaluation of 17α-ethinylestradiol effects.

Weiserova Z, Zentrichova V, Medkova D, Blahova J, Franc A, Garajova M, Mares J, Postulkova E, Franek R, Psenicka M, Marsalek P, Svobodova Z.

Journal Article 2022; 43(5): 281-290 PubMed PMID: 36584404

OBJECTIVES: We tested the toxicity of ethinylestradiol, a semisynthetic estrogen used in oral contraceptives, on all-male triploid zebrafi.....

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Articles by author - Zdenka Svobodova

Oxidative detoxication of carcinogenic 2-nitroanisole by human, rat and rabbit cytochrome P450.

Severe chronic lithium intoxication in patient treated for bipolar disorder.

The effect of silver nanoparticles and silver ions on zebrafish embryos (Danio rerio).

Use of all-male triploid population of zebrafish (Danio rerio) for evaluation of 17α-ethinylestradiol effects.