Articles by author - Josef Tomandl

Evaluation of the activity of P450 enzymes in rats: use of the single marker or combined drug administration.

Jurica J, Kyr M, McCaskey Hadasova E, Tomandl J.

Journal Article 2009; 30(Suppl 1): 92-95 PubMed PMID: 20027151  Keywords:  Animals, Biotransformation, Cytochrome P-450 Enzyme System:chemistry, Liver:drug effects, Male, Phenacetin:metabolism, Rats, Rats, Wistar, Time Factors, Tolbutamide:metabolism,.    Citation

OBJECTIVES: A "cocktail" of several substrates is frequently used to assess metabolic activity of multiple cytochrome P450 enzymes in one .....

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