Peptide Epitalon activates chromatin at the old age. Khavinson V, Lezhava T, Monaselidze J, Jokhadze T, Dvalishvili N, Bablishvili N, Trofimova S. Journal Article 2003; 24(5): 329-333 PubMed PMID: 14647006 Keywords: Aged, Aging:physiology, Cells, Cultured, Euchromatin:drug effects, Heterochromatin:drug effects, Hot Temperature, Humans, Lymphocytes:cytology, Oligopeptides:pharmacology, Protein Denaturation, Ribosomal Proteins:genetics, Transcriptional Activation:drug . Citation UNLABELLED: OBJECTIVES and design. We have studied the effect of synthetic peptide Epitalon on the activity of ribosomal genes, denaturati..... Read abstract
Pineal-regulating tetrapeptide epitalon improves eye retina condition in retinitis pigmentosa. Khavinson V, Razumovsky M, Trofimova S, Grigorian R, Razumovskaya A. Clinical Trial 2002; 23(4): 365-368 PubMed PMID: 12195242 Keywords: Adolescent, Adult, Aged, Animals, Electric Conductivity, Electroretinography, Humans, Middle Aged, Oligopeptides:administration & dosage, Pineal Gland:drug effects, Rats, Rats, Inbred Strains, Retina:pathology, Retinitis Pigmentosa:drug therapy,. Citation : We have studied the effect of tetrapeptide Epitalon (Ala-Glu-Asp-Gly) on the course of congenital pigmented degeneration of the retina. ..... Read abstract