Articles by author - Eduard Ujházy

Newborn with neonatal form of molybdenum cofactor deficiency - the first patient in the Slovak Republic.

Brucknerova I, Behulova D, Bzduch V, Mach M, Dubovicky M, Ujhazy E.

Case Reports 2010; 31(Suppl 2): 5-7 PubMed PMID: 21187823  Keywords:  Disease Progression, Fatal Outcome, Humans, Incidence, Infant, Newborn, Male, Metal Metabolism, Inborn Errors:complications, Molybdoferredoxin, Neurodegenerative Diseases:diagnosis, Slovakia:epidemiology,.    Citation

OBJECTIVE: To present the case of a term newborn with rapid progression of signs of neurodegenerative disease.

RESULTS:.....

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Maternal treatment of rats with the new pyridoindole antioxidant during pregnacy and lactation resulting in improved offspring hippocampal resistance to ischemia in vitro.

Gáspárová Z, Snirc V, Stolc S, Dubovický M, Mach M, Ujházy E.

Journal Article 2010; 31(3): 348-352 PubMed PMID: 20588238  Keywords:  Action Potentials:drug effects, Animals, Antioxidants:therapeutic use, Brain Ischemia:prevention & control, Female, Hippocampus:drug effects, In Vitro Techniques, Indoles:therapeutic use, Lactation, Pregnancy, Pregnancy Complications, Cardiovascular:drug .    Citation

OBJECTIVE: Damage to the developing brain may be caused by maternal environment, nutritional deficiencies, failure of protective mechanism.....

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Effect of the new pyridoindole antioxidant SMe1EC2 on functional deficits and oedema formation in rat hippocampus exposed to ischaemia in vitro.

Gáspárová Z, Janega P, Babál P, Snirc V, Stolc S, Mach M, Ujházy E.

Journal Article 2009; 30(5): 574-581 PubMed PMID: 20035262  Keywords:  Animals, Antioxidants:pharmacology, Brain Ischemia:drug therapy, Edema:drug therapy, Electrophysiology, Female, Hippocampus:cytology, Humans, Indoles:pharmacology, Male, Neuroprotective Agents:pharmacology, Pyridines:pharmacology, Rats, Rats, Wistar,.    Citation

OBJECTIVES: The idea of neuroprotective therapy for ischaemic stroke is based on results from studies on experimental animal models of bra.....

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Conjugated hyperbilirubinaemia as the first manifestation of mevalonic aciduria in a term newborn.

Brucknerova I, Behulova D, Sebova C, Bzduch V, Mach M, Dubovicky M, Ujhazy E.

Case Reports 2009; 30(Suppl 1): 29-31 PubMed PMID: 20027140  Keywords:  Diagnosis, Differential, Humans, Hyperbilirubinemia, Neonatal:diagnosis, Infant, Newborn, Male, Mevalonate Kinase Deficiency:complications,.    Citation

OBJECTIVES: To present clinical and laboratory findings in the case of a term newborn with conjugated hyperbilirubinaemia and to stress th.....

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Prenatal developmental toxicity study of the pyridoindole antioxidant SMe1EC2 in rats.

Ujhazy E, Dubovicky M, Ponechalova V, Navarova J, Brucknerova I, Snirc V, Mach M.

Journal Article 2008; 29(5): 639-643 PubMed PMID: 18987587  Keywords:  Abnormalities, Drug-Induced:pathology, Animals, Antioxidants:toxicity, Female, Fetal Development:drug effects, Fetal Diseases:chemically induced, Indoles:toxicity, Neuroprotective Agents:toxicity, Pregnancy, Pyridines:toxicity, Rats, Rats, Wistar, Reprodu.    Citation

OBJECTIVE: The 2-ethoxycarbonyl-8-methoxy-2,3,4,4a,5,9b-hexahydro-1H-pyrido-[4,3b] indolinium chloride (SMe1EC2) is a prospective antioxid.....

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Reversible asphyxial status in a newborn due to neonatal form of carnitine palmitoyltransferase II deficiency.

Brucknerova I, Bzduch V, Behulova D, Ferianec V, Dubovicky M, Ujhazy E, Mach M.

Case Reports 2008; 29(5): 627-630 PubMed PMID: 18987586  Keywords:  Asphyxia Neonatorum:enzymology, Cardiopulmonary Resuscitation, Carnitine O-Palmitoyltransferase:deficiency, Heart Failure:etiology, Humans, Infant, Newborn, Male, Respiratory Insufficiency:etiology, Tandem Mass Spectrometry,.    Citation

OBJECTIVES: To present a term newborn with severe asphyxial status due to dysrrhythmia induced by the neonatal form of carnitine palmitoyl.....

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