Articles by author - Katarina Valachova

Effect of venlafaxine on scavenging free radicals in vitro.

Plachá K, Valachová K, Rapta P, Topol'ská D, Melichercíková K, Soltés L.

Journal Article 2016; 37(1): 59-64 PubMed PMID: 26994387  Keywords:  Electron Spin Resonance Spectroscopy, Electrons, Free Radical Scavengers:chemistry, Hydroxyl Radical:chemistry, Oxidation-Reduction, Superoxides:chemistry, Time Factors, Venlafaxine Hydrochloride:chemistry,.    Citation

UNLABELLED: O BJECTIVE: Venlafaxine (VLF) was examined as a potential donor of H atom(s) to scavenge hydroxyl and peroxy-type radicals gen.....

Read abstract  Full text PDF

Radical scavenging activity of Caesalpinia spinosa.

Valachová K, Topol'ská D, Nagy M, Gaidau C, Niculescu M, Matyašovský J, Jurkovič P, Soltés L.

Journal Article 2014; 35(Suppl 2): 197-200 PubMed PMID: 25638387  Keywords:  Antioxidants:pharmacology, Caesalpinia, Hyaluronic Acid:metabolism, Plant Extracts:pharmacology,.    Citation

OBJECTIVES: To assess protective effects of the tara (Caesalpinia spinosa) extract against hyaluronan (HA) degradation evoked by .....

Read abstract  Full text PDF

Determination of antioxidative properties of herbal extracts: Agrimonia herba, Cynare folium, and Ligustri folium.

Topolska D, Valachova K, Nagy M, Soltes L.

Journal Article 2014; 35(Suppl 2): 186-190 PubMed PMID: 25638386  Keywords:  Agrimonia, Antioxidants:pharmacology, Cynara, Hyaluronic Acid:metabolism, Ligustrum, Plant Preparations:pharmacology,.    Citation

OBJECTIVES: Hyaluronan (HA) molecules were exposed to free radical-mediated degradation performed by the reaction mixture Cu(II) .....

Read abstract  Full text PDF

Free-radical degradation of high-molar-mass hyaluronan induced by Weissberger's oxidative system: potential antioxidative effect of bucillamine.

Banasova M, Sasinkova V, Mendichi R, Perecko T, Valachova K, Juranek I, Soltes L.

Journal Article 2012; 33(Suppl 3): 151-154 PubMed PMID: 23353859  Keywords:  Antioxidants:chemistry, Ascorbic Acid:chemistry, Copper:chemistry, Cysteine:analogs & derivatives, Extracellular Matrix:chemistry, Free Radicals:chemistry, Humans, Hyaluronic Acid:chemistry, Molecular Weight, Oxidation-Reduction, Spectroscopy, Fourier Tra.    Citation

OBJECTIVES: Hyaluronan (HA), one of the main components of extracellular matrix, is a glycosaminoglycan composed of repeating disaccharide.....

Read abstract  Full text PDF

Ascorbate and Cu(II)-induced oxidative degradation of high-molar-mass hyaluronan. Pro- and antioxidative effects of some thiols.

Valachova K, Hrabarova E, Drafi F, Juranek I, Bauerova K, Priesolova E, Nagy M, Soltes L.

Journal Article 2010; 31(Suppl 2): 101-104 PubMed PMID: 21187839  Keywords:  Antioxidants:pharmacology, Ascorbic Acid:pharmacology, Copper:pharmacology, Cysteamine:pharmacology, Dose-Response Relationship, Drug, Glutathione:pharmacology, Hyaluronic Acid:metabolism, Hydrogen Peroxide:metabolism, Hydroxides:metabolism, Oxidation-Red.    Citation

OBJECTIVE: This study presents the results of antioxidative and pro-oxidative efficacy of cysteamine and D-penicillamine (D-pen) in compar.....

Read abstract  Full text PDF

Carnosine inhibits degradation of hyaluronan induced by free radical processes in vitro and improves the redox imbalance in adjuvant arthritis in vivo.

Drafi F, Bauerova K, Valachova K, Ponist S, Mihalova D, Juranek I, Boldyrev A, Hrabarova E, Soltes L.

Journal Article 2010; 31(Suppl 2): 96-100 PubMed PMID: 21187837  Keywords:  Animals, Antioxidants:pharmacology, Antirheumatic Agents:pharmacology, Arthritis, Experimental:drug therapy, Carnosine:pharmacology, Disease Models, Animal, Free Radicals, Glutathione:metabolism, Hyaluronic Acid:metabolism, In Vitro Techniques, Male, Meth.    Citation

OBJECTIVE: New ways of supplementary or combinatory therapy of rheumatoid arthritis (RA) are of great importance. The aim is to find an ad.....

Read abstract  Full text PDF