Dot1L mediated histone H3 lysine79 methylation is essential to meiosis progression in mouse oocytes.

Journal Article 2014; 35(6): 523-530 PubMed PMID: 25433842 Keywords: Acetylation, Animals, Female, Histones:genetics, Meiosis:physiology, Methylation, Methyltransferases:genetics, Mice, Inbred ICR, Oocytes:cytology, Protein Processing, Post-Translational:physiology, RNA, Messenger:genetics, RNA, Small Interfering:genetics,.

OBJECTIVES: Post-translational modifications of lysine residues of histones can result in a series of functional changes. Lysine 79 of his.....

Identifying distinct candidate genes for early Parkinson's disease by analysis of gene expression in whole blood.

Journal Article 2014; 35(5): 398-404 PubMed PMID: 25275262 Keywords: AMP-Activated Protein Kinases:genetics, Adaptor Proteins, Signal Transducing:genetics, Age of Onset, DEAD-box RNA Helicases:genetics, Early Diagnosis, Gene Regulatory Networks, Genetic Markers, Humans, Membrane Proteins:genetics, Minor Histocompatibility .

OBJECTIVE: Parkinson disease (PD) is a degenerative disorder of the central nervous system, and in the majority of cases, the causes of PD.....

Journal Article 2014; 35(5): 385-392 PubMed PMID: 25275260 Keywords: Animals, Basolateral Nuclear Complex:cytology, Dopamine:metabolism, Dopamine Agents:metabolism, Dopamine Antagonists:pharmacology, Dopaminergic Neurons:physiology, Excitatory Postsynaptic Potentials:drug effects, Male, Organ Culture Techniques, Presynapti.

OBJECTIVES: Dopaminergic signaling in the basolateral amygdala (BLA) is important for emotion-related activity. However, little is known a.....

Journal Article 2014; 35(5): 417-426 PubMed PMID: 25275258 Keywords: Amygdala:metabolism, Animals, Brain:metabolism, Corticotropin-Releasing Hormone:metabolism, Dorsal Raphe Nucleus:metabolism, Fluorescent Antibody Technique, Hippocampus:metabolism, In Situ Hybridization, Locus Coeruleus:metabolism, Male, Median Eminence:m.

OBJECTIVES: To investigate whether CRHR1 and CRHR2 are colocalized in CRH-specific neurons in rat brain.

METHODS: .....