Articles by author - Li-hua Yu

The ABCD2 score may underestimate the short-term risk of stroke in Chinese population: A meta-analysis.

Chu T, Yu W, Wang Y, Guo N, He J, Shao Y, Mang J, Xu Z.

Journal Article 2015; 36(3): 262-268 PubMed PMID: 26313394  Keywords:  China:epidemiology, Humans, Ischemic Attack, Transient:epidemiology, Severity of Illness Index, Stroke:diagnosis,.    Citation

OBJECTIVES: The ABCD2 score has been commonly used to triage patients with transient ischemic attack (TIA) who are at high risk for immine.....

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Damage to vascular endothelial cells by high insulin levels is associated with increased expression of ChemR23, and attenuated by PPAR-gamma agonist, rosiglitazone.

Hao F, Mu J, Zhang H, Kuang H, Yu Q, Bai M, Meng P.

Journal Article 2015; 36(1): 59-66 PubMed PMID: 25789586  Keywords:  Anilides:pharmacology, Cells, Cultured, Human Umbilical Vein Endothelial Cells:drug effects, Humans, Hypoglycemic Agents:pharmacology, Insulin:pharmacology, PPAR gamma:agonists, Receptors, Chemokine:metabolism, Thiazolidinediones:pharmacology,.    Citation

OBJECTIVE: This study investigated the effect of different insulin concentrations on the activity of vascular endothelial cells (VECs), an.....

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Identifying distinct candidate genes for early Parkinson's disease by analysis of gene expression in whole blood.

Sun A, Wang J, Shan Y, Yu W, Li X, Cong C, Wang X.

Journal Article 2014; 35(5): 398-404 PubMed PMID: 25275262  Keywords:  AMP-Activated Protein Kinases:genetics, Adaptor Proteins, Signal Transducing:genetics, Age of Onset, DEAD-box RNA Helicases:genetics, Early Diagnosis, Gene Regulatory Networks, Genetic Markers, Humans, Membrane Proteins:genetics, Minor Histocompatibility .    Citation

OBJECTIVE: Parkinson disease (PD) is a degenerative disorder of the central nervous system, and in the majority of cases, the causes of PD.....

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Insulin inhibits Abeta production through modulation of APP processing in a cellular model of Alzheimer's disease.

Wang X, Yu S, Gao S, Hu J, Wang Y, Liu H.

Journal Article 2014; 35(3): 224-229 PubMed PMID: 24977973  Keywords:  Alzheimer Disease:genetics, Amyloid Precursor Protein Secretases:genetics, Amyloid beta-Peptides:antagonists & inhibitors, Amyloid beta-Protein Precursor:metabolism, Cells, Cultured, Gene Expression Regulation, Enzymologic:drug effects, Humans, Insulin:ph.    Citation

OBJECTIVE: Amyloid-beta (Abeta) is a 36-43 amino acid peptide that is derived by processing of the beta-amyloid precursor protein (APP). A.....

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Estrogen altered facial mechanical pain threshold and trigeminal P2X3 receptor expression.

Yu L, Li N, Liu C, Ma B.

Journal Article 2011; 32(6): 811-815 PubMed PMID: 22286789  Keywords:  Animals, Behavior, Animal:physiology, Estradiol:pharmacology, Estrogens:pharmacology, Facial Pain:physiopathology, Female, Male, Ovariectomy, Pain Measurement, Pain Threshold:drug effects, RNA, Messenger:metabolism, Random Allocation, Rats, Rats, Sprague-.    Citation

OBJECTIVES: P2X3 receptors are expressed in trigeminal ganglia (TG) and participate in the transduction of facial pain. However, the mecha.....

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